Hormone therapy for transgender patients
Abstract
Many
transgender men and women seek hormone therapy as part of the
transition process. Exogenous testosterone is used in transgender men to
induce virilization and suppress feminizing characteristics. In
transgender women, exogenous estrogen is used to help feminize patients,
and anti-androgens are used as adjuncts to help suppress masculinizing
features. Guidelines exist to help providers choose appropriate
candidates for hormone therapy, and act as a framework for choosing
treatment regimens and managing surveillance in these patients.
Cross-sex hormone therapy has been shown to have positive physical and
psychological effects on the transitioning individual and is considered a
mainstay treatment for many patients. Bone and cardiovascular health
are important considerations in transgender patients on long-term
hormones, and care should be taken to monitor certain metabolic indices
while patients are on cross-sex hormone therapy.
Keywords: Hormone therapy, transgender, gender dysphoria, cross-sex hormones
Conclusions
Many
transgender individuals seek cross-sex hormone therapy for treatment of
gender dysphoria. Hormone therapy plays an integral role in the
transition process for patients. Guidelines exist to help providers
prescribe and monitor therapy. Hormone therapy has been shown to be
associated with positive outcomes for patients, but there are important
metabolic implications of therapy that must be carefully considered when
treating patients.
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